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At these timepoints most cells contained both small and large accumulations of Atx1[2Q]GFP, Atx1[85Q]GFP and NLS[Q64]GFP.
Consequently most cells contained one fully replicated chromosome (Figure 1A) where t = −1 is one minute before the downshift to 30°C.
During this period ongoing chromosomal replication was completed in the dna mutants and the majority of cells divided so that most cells contained one genome equivalent.
Most cells contained a mixture of univalents, bivalents and chromosome fragments, presumably giving rise to the polyads with variable numbers of nuclei.
While fluorescence in A1 and A2 cells resembled that of wild type cells, A3 and A4 cells had dimmer overall fluorescence and most cells contained one or two small bright foci.
When replication was allowed to proceed to completion at permissive temperature, most cells contained two fully replicated chromosomes and some had three and four chromosomes but very few had only one (Figure 4B).
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Most cells contain many mitochondria, each roughly the size of a bacterium, ranging from 0.5 to 10 m (micrometre; 1 m = one-millionth of a metre) in diameter; their size and shape differ depending on the cell type in which they occur.
Most cells contain the same set of genes, and yet they are extremely diverse in appearance.
At medium induction levels (12.5 μM, Figure 4E), most cells contain mRNA, and many are actively transcribing.
Most cells contain approximately 1 × 106 Hmoleculescules in their nuclei [ 34], which may be translocated actively to the cytoplasm upon stimulation or passively by necrotic cells.
During doxorubicin resistance development, the composition of the population in each cell line shifted with increasing resistance, from a population in which most cells contain three TopoII alpha gene copies (GLC4) to a population in which most cells contain only two copies.
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