They were also shown to decrease the possible cytotoxic effect of the active agents on most cell lines tested.
Most cell lines currently used for biopharmaceutical manufacturing contain a constitutive expression unit stably integrated in the target chromosome.
For comparison, acute 13 mmHg pO2 in most cell lines decreases the radiosensitivity by only a factor of about 1.2 versus normoxic conditions ([44], Figure 3).
Furthermore, it was also found that the N-alkyl substituted derivatives were more potent than the N-aryl and N-benzyl substituted compounds against most cell lines.
On most cell lines, oncolysis was significantly improved with replicating viruses in comparison to Ad5luc1.
For most cell lines, the nc-rRNA was also negatively correlated with the total 45S rRNA.
Most cell lines derived from EC undergo apoptosis upon exposure to very low concentrations of Cisplatin.
As expected, guanosine treatment alone had no significant effect on virus replication (Fig. 5) in most cell lines.
Most cell lines were tested between four and six times for the expression of NKp30L and NKp44L in independent experiments.
This contrasts with our qRT-PCR data in which we saw robust CTCF expression but undetectable BORIS levels in most cell lines and tissues.
Remarkably, unsupervised clustering of both rosette and far-Western data revealed that most cell lines with strong MET activation cluster in a distinct, tight group (Fig. 5B&C).
