Sentence examples for most cell cycle from inspiring English sources
It is well established that most cell cycle regulators are degraded by the ubiquitin-proteasome system (UPS) [1], [17].
The SPB increases in size late in the cell cycle and during most cell cycle arrests and exchanges components during G1/S.
In general, the elucidation of the role of GSH in the cell proliferation was approached by the determination of its overall cellular content, although it is the nucleus where most cell cycle progression events take place.
As with most cell cycle regulatory proteins, Ki67 expression is tightly regulated, appearing in mid G1 with a half-life of 60 to 90 minutes [ 7].
Most cell cycle analyzes make use of cell synchronization methods to enrich populations of cells at specific cell cycle stages in sufficient quantities for biochemical characterization.
Indeed we observe that although most cell cycle protein complexes retain cell cycle-regulated genes in both species, the identity of dynamic members differs between species (Additional file 3: Figure S4).
Most cell cycles contain additional gap phases between S and M phases, which provide additional time for growth and also serve as important regulatory transitions, through which progression to the next cell-cycle stage can be controlled by intracellular and extracellular signals (Nigg, 2001; Sherr and Roberts, 2004).
Similar to most cell-cycle proteins, the expression of c-Fos, Fra-1, Fra-2 and, to a lesser degree, FosB is absent or weak in normal mammary tissue samples, and the data obtained from Western blots with breast cancer specimens probably reflect their expression in tumour cells (Bamberger et al, 1999).
We thus conclude that distal-most cells cycle more slowly for the most part because they spend more time in G2.
We selected PD173074 for in vivo assessment as it was the most potent and selective compound, with the lowest IC50 values and the most pronounced cell cycle and apoptotic effects in vitro.
Of these, most likely, cell cycle synchronization [ 7, 60, 61] and DNA repair [ 32] play an important role in the radiosensitisation.
