In most cases, sample sizes have been small and the study population highly selected and non-representative of the general population.
In most cases, samples with calculated values greater than the cutoff values were omitted as outliers.
In most cases, samples with high anti-Neu5Gc IgG concentration also exhibited relatively high IgM concentration.
We do not have formal disease activity measurements for the patients with these other diseases but in most cases, samples were taken when patients were symptomatic.
Private haplotypes could also represent haplotypes that went undetected in other sky islands due to limited sampling, but we believe this is unlikely because in most cases sample sizes were high relative to the number of haplotypes.
However, we need to stress the fact that the effect of collectors and species could not be differentiated since in most cases samples from one species were collected by a single person under unique conditions (Additional file 1: Table S1).
Assuming that in most cases samples were taken a few days before to just after the death of the host, we think these dates represent acceptable, though not ideal, estimates of the endpoint of strain time.
In most cases, samples contained few multinucleated cells, amounting to less than 1% of the nevus cell population, although some nevi showed a higher abundance of these abnormal cells, reaching up to 23%.
In most cases, samples were collected straight from the anus of the defecating dolphin on deck of the research vessel, however, in 2006 three samples were scooped from the water in 50 ml falcon tubes, where the dolphins were being handled and sea water was drained by fastening the tube cap loosely and inverting.
We measured levels of 8-oxo-dG indicative of oxidative DNA damage in two to five randomly selected mice for each treatment category and time point up to 1 year; in most cases, samples from the median and left liver lobes were analyzed for each mouse.
