Then, each individual sample is processed for the identification of metabolites which, in most cases, involves the comparison of individual spectra to standard reference libraries.
The most commonly used application of viral vectors in the central nervous system (CNS) is gene therapy, which in most cases involves delivery of a normal copy of a defective gene but may also involve the knockdown of deleterious functions.
But sometimes, we are so excited about the innovation (and the technology involved) that we forget that our goal is to solve a problem--a pressing problem that in most cases involves humans.
Multiple sclerosis (MS) is an inflammatory and demyelinating disease of the central nervous system, which in most cases involves motor, sensory, visual and cognitive alterations, besides other clinical manifestations [ 1, 2].
Liver damage is a widespread pathology which in most cases involves oxidative stress and is characterized by a progressive evolution from steatosis to chronic hepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma [ 2].
The mechanism of OP neurotoxicity in most cases involves overstimulation of postsynaptic cholinergic receptors after inhibition of AChE (Keifer and Mahurin, 1997), although other macromolecular targets may also be involved (Pope 1999).
