Sentence examples for most broadly conserved from inspiring English sources

Even the most broadly conserved NAP, Hu or its homologue IHF, is absent in Leptospira interrogans and Corynebacterium diphtheriae.

The most broadly conserved is PPM8, which is part of a group containing human and yeast pyruvate dehydrogenase PP.

Although the HA1/HA2-joining region is the most broadly conserved HA sequence, other determinants on HA2 are shared between a restricted number of subtypes.

MiR-199a-5p is one of the most broadly conserved miRNAs and is generally believed to be a multifunctional miRNA involved in the regulation of angiogenesis, cell proliferation, autophagy, and many other cell functions.

In particular, some of the ideas put forth are rather SYCP3-centric – the model presented in Figure 6 suggests that SYCP3 might suffice to organize naked DNA, but in fact cohesins are the most broadly conserved and essential axis components, SYCP3 normally only interacts with chromosomes in the presence of cohesins, so its organizational role presumably depends on this context.

Of these, the most broadly conserved protein is the CCCTC-binding factor, CTCF [ 22].

While we do not wish to question their validity or understate their potential, we argue that most miRNA functions will be covered by the most highly expressed or broadly conserved miRNAs, which were already present in earlier versions of miRBase and thus represented in our library.

conservation of miRNA: broadly conserved = conserved across most vertebrates, typically up to zebrafish; conserved = conserved across most mammals, but typically not beyond placental mammals; or poorly conserved = all others; and the threshold of the total context site, defined as the sum of context scores for the most favourable (most negative) miRNA in this family.

However, most of these ORFs are not broadly conserved, which has brought into question their potential functionality.

Most co-expression modules have strong phylogenetic signals, with broadly conserved genes and clade-specific genes predominating different substructures of the cell cycle co-expression network.

The microRNAs upregulated with increasing emphysema severity included broadly conserved and poorly conserved microRNAs, with the most upregulated including miR-520e and miR-302d from the miR-93 family, miR-92a, miR-638, miR-211, and miR-150.