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Comparison of the z-scores allowed the most biased nucleotide sub-pattern responsible for the bias of the codon pair to be identified.
The skew value is the farthest of all from the coordinates, meaning this proturan mitogenome has the most biased nucleotide composition ever reported for arthropods.
Compared with other metazoan mtDNA, it has the most biased nucleotide composition with T = 52.4%, an extreme and reversed AT-skew of -0.351 and a GC-skew of 0.350.
The NC64A viruses have the most biased nucleotide composition of all the CVs (i.e., 40% G + C), which may explain why these viruses require a higher degree of control of the available nucleotide pool.
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Among the most important features are biased nucleotide composition favoring adenine-thymine bases and rapid sequence evolution.
This could also reflect the fact that most TE-derived sequences examined were previously non-coding (this is certainly true for Alu-derived exons) and had a biased nucleotide composition (Alus for example are GC-rich) prior to exonization.
The most sensitive outcome could be the most biased.
Nevertheless, although the most breed – biased genes tend to be also sex biased, the most sex biased genes are not among the most breed biased genes.
The 5' nucleotide of the 24nt species was biased towards adenine while uracil was most frequent nucleotide at the 5' end of 21nt species, as reported previously [ 15, 52].
Most of the few populational studies in this area are biased towards single nucleotide variants (SNV) [ 3, 9, 11].
As with other flatworm mtDNAs, the nucleotide compositions of the new sequences are biased toward T and A, with T being the most favored nucleotide and C the least favored [ 46].
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