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As the ancestor subtype, HLA-B ∗ 2705 was most common type in Europe and America, so most basic researches including gene cloning and transgenic animals were about HLA-B ∗ 2705 subtype.
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But there was, equally, not even the most basic research.
What's more, the number of misconceptions propagated about the most basic research can be staggering.
It's just plain foolish, as well as comically arrogant, to ignore all this, to fail to do the most basic research.
What could we learn from giant squid about neurology, evolution, ecosystems, etc.? As with most basic research, it is hard to know the benefits until the research is actually done; there is always a gamble in whether such discoveries will have practical rewards.
Like most basic research positions, plant-research positions within academia and federal research labs are highly competitive.
It appears that for most basic research applications, cleavage activity can be maximized and off-targets minimized by carefully choosing guide RNAs based on computational predictions.
The study is a limited one, they are quick to point out, but there is essentially nothing else on the topic and even the most basic research is warranted.
Russia's Ministry of Education and Science has been trying to introduce such a system since the fall of the Soviet Union but has been hampered by RAS, which has controlled most basic research in Russia.
As a result, it was believed that such disclosure was not an obligation or responsibility on the part of investigators, in addition to the fact that data accuracy obtained in most basic research is generally not sufficiently high to qualify as clinical grade.
Most basic research towards this goal has been focused on achieving donor specific tolerance by blocking putative 'co-stimulatory' signals.
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