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Today, I believe most are necessary.
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Most revolutions are necessary, most end up betraying the ideals they claimed to represent, and most revolutionaries are at least mildly sociopathic.
Higher dose requirements for most antidepressants are necessary to avoid subtherapeutic blood concentrations.
Therefore, in silico methods to help biologists select the most meaningful sRNAs are necessary.
So, most effective rejection methods are necessary.
In most cases, these structures are necessary for cell function and are thus evolutionarily conserved.
Most other IFT proteins are necessary to assemble cilia/flagella in the first place.
However, further studies to reveal the exact function of most of these genes are necessary.
In most cases, drug combinations are necessary to cope with these symptoms [ 2, 3].
Most of these discontinuations are necessary within the first weeks of treatment [ 3].
More rigorous studies to determine which score is most valid and reliable are necessary to provide a conclusive recommendation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com