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This strategy circumvents the need for the isolation of pure compounds via extensive activity-guided fractionation, usually the most arduous part of identifying a new bioactive metabolite.
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Widely known for creating the role of Crown Prince Rudolf in Kenneth MacMillan's ballet Mayerling – possibly the most arduous for a male dancer in the entire dance repertory – he was also outstanding in classical, romantic and humorous parts.
Peeling is the most arduous chore here.
Technically, it is a long and arduous part.
But the last mile may be the most arduous.
His most arduous adventures, though, were intellectual in nature.
"Committed" wound up being her most arduous project.
The test begins with the most arduous start to any major championship.
He travelled by night, taking the highest passes and following the most arduous paths.
Among widespread chronic conditions, diabetes is arguably the most arduous to control.
Second Platoon, Company B has endured one of the most arduous assignments in Afghanistan.
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