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Parameter estimates and model fit for the fixed effects, item-based SF36 to AQoL algorithm are reported in Table 2. Respondent-specific fixed effects were again significantly greater than zero (F = 1.85, df = (640,429), p < 0.000) and the Hausman test (χ2 = 55.32, df = 10, p < 0.000) again suggested that the fixed effects model most appropriately characterised respondent-specific effects.
For the 'low severity' algorithm, respondent-specific fixed effects were significantly greater than zero (F = 2.14, df = (566,364), p < 0.000) and the Hausman specification test (χ2 = 33.92, df = 10, p < 0.000) suggested that the fixed effects model most appropriately characterised respondent-specific effects.
For the 'low severity' algorithm, respondent-specific fixed effects were significantly greater than zero (F = 2.05, df = (567,363), p < 0.000) and the Hausman test (χ2 = 46.64, df = 11, p < 0.000) suggested that the fixed effects model most appropriately characterised respondent-specific effects.
Parameter estimates and model fit for the subscale-based SF36 algorithm are reported in Table 2. Respondent-specific fixed effects were again significantly greater than zero (F = 2.01, df = (639,431), p < 0.000) and the Hausman specification test (χ2 = 39.87, df = 8, p < 0.000) again suggested that the fixed effects model most appropriately characterised respondent-specific effects.
The Hausman test suggested that the fixed effects model most appropriately characterised respondent-specific effects in the NIHSS = 0 and NIHSS = 1 5 (χ2 = 49.53, df = 2, p < 0.000) subgroups whereas the additional assumptions required for the random effects model were met in the NIHSS ≥ 6 subgroup (χ2 = 0.83, df = 2, p = 0.660).
For the item-based NIHSS algorithms, the Hausman test suggested that the fixed effects model most appropriately characterised respondent-specific effects for the all stroke (χ2 = 40.24, df = 2, p < 0.000), NIHSS = 0 5 (χ2 = 23.82, df = 2, p < 0.000) and NIHSS ≥ 6 (χ2 = 76.61, df = 9, p = 0.000) algorithms.
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An Emax function most appropriately characterized the biomarker ANC relationship.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com