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Studies that were multiply published were checked and the most appropriate trial data extracted.
Taking this view, researchers are obliged to minimise the risks consistent with using the most appropriate trial design [ 13], which in surgery, may be a PCST in order to answer questions about efficacy.
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The challenge is to build the most appropriate trials to validate these hypotheses.
Classifying gastric cancer patients by these signature genomic alterations may facilitate patient allocations to the most appropriate clinical trials, thereby maximising patient participation in combatting this lethal disease.
Prospective randomised controlled trials remain the most appropriate instrument to test the efficacy of CT screening in heavy smokers.
This focus group selected the most appropriate measures to test in the pilot trial.
Arguably, though, it is the case that most strongly demonstrates the need for a UK judge to determine the most appropriate forum for a trial, something which is currently precluded by the Extradition Act 2003.
Coming up with the right concept, writing the great script, CASTING the right talent, hiring the most appropriate director — all take trial, error, revision, time and money.
It makes little sense to perform a randomized trial to assess the cost-effectiveness of a rapidly morphing technology, whereas patient outcomes and/or cost-effectiveness may be the most appropriate endpoints for a trial of a technology for which reader performance (i.e. accuracy) has been well established.
Further studies are needed to establish measurement properties of standardised field tests for individuals with NSCLC to allow the most appropriate choice of test when designing research trials.
Informative IPAs may be useful for suggesting therapeutic targets or to select the most appropriate patients for clinical trials.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com