Sentence examples for most appropriate tissue from inspiring English sources

Attempts at exhaustive scans for imprinted genes in humans have encountered several drawbacks, including the challenge of using the most appropriate tissue and developmental stage, a problem exacerbated by reliance on lymphoblastoid cell lines (LCLs) [4].

For our purposes, whole blood seemed the most appropriate tissue to track seasonal dietary patterns, given its relatively rapid turnover integrating short-term dietary variation in terms of days or weeks [20] [22].

Consequently, we focused only on the skeletal muscle as the most appropriate tissue for deriving the predictive models of interest.

There is further evidence that classical T cell assays will have to be used to measure responses in the most appropriate tissue compartment [ 17, 18].

One important question under debate is to define in MCRC patients, the most appropriate tissue on which DNA analysis should be performed in the context of targeted therapies.

Ideally, methylation changes in NOS genes should be evaluated in the most appropriate tissue for the outcome of interest in order to study functional consequences.

These genetic drivers of ASM can be identified in easy accessible tissue, which can then be followed up in the most appropriate disease-related tissue to examine for any surrounding CpG modulation.

Firstly, we needed to determine the most appropriate engrafted xenograft tissue for analysis.

However, such analysis must take note of what is known of the pathophysiology of the disease, because the most appropriate cell or tissue type needs to be considered given the context-specificity of gene regulation and functional variants.

From a mechanical point of view, it is likely that a strain-based model could be the most appropriate to describe tissue failure, as suggested in other studies on cortical bone where a strain-controlled failure was proposed [ 46].

According to the results of the experiments, the nanocomposite scaffold with modified composition (Cs/BG/CNT, 80 20 2 wt%) was the best one in matters of mechanical, chemical, and cellular properties and also the most appropriate for trabecular bone tissue.