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Accordingly, rhodopsin was selected as the most appropriate template for modelling the structure of the ECL2 of the TSHR TMD.
This workflow was applied to a set of 14 human family A GPCRs suggesting for each the most appropriate template(s) for building a comparative molecular model.
Using key features a workflow has been formulated for identifying the most appropriate template(s) for building homology models of GPCRs of unknown structure.
The aim of this study is to provide a rational workflow for selecting the most appropriate template(s) for building comparative models of GPCRs with no experimentally determined structure.
The color scheme helps to find the most appropriate template as well, and we have added a description on the figure legend as well.
The best predicted 3D structure of the protein was structurally aligned with the most appropriate template (PDB code: 3qlB) by Dali [ 40, 41] at http://ekhidna.biocenter.helsinki.fi/dali_server/.fi/dali_server/
Similar(54)
Three types of SAM-covered substrates, that is, CH3-, CHO-, and COOH-terminated substrates, were investigated to find the most appropriate chemical template for the MTP of SnOx.
By examining the immediate bonding environment of an atom, it is often possible to make a reasonable estimate as to which of these geometry templates is most appropriate - and more importantly, which would be most appropriate in the context of adding an additional bond to a new atom.
Since periodic perceptual grouping based on matching sound events to pulse driven template structures represents the most appropriate basis for a definition of musical rhythm, rhythmic synchronization tasks would be one of the most meaningful and realistic experimental paradigms to approach the study of the neural correlates of rhythm.
Choose the one most appropriate and make sure to select a template in the correct size as your labels.
The implant size used was chosen by the surgeon as the most appropriate for each patient after preoperative digital templating had been performed.
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