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Ideally, further research is needed to decide on the most appropriate targets and configurations of protected areas and their likely influence on seabird populations e.g. [51].
It sounds feasible to reason that in the future, those genotypes with shortest times to incident infections (i.e., the highest IRs), could be the most appropriate targets for early prevention, e.g. by genotype-specific multivalent HPV vaccines.
Besides, given that DNA damage might elicit pyocin production, cells with damaged DNA may be the most appropriate targets for cell death, enabling preservation of the remainder of the population.
Importantly, phylogenetically conserved steps of the infection process can be ruled out as major factors in coevolution, but are, perhaps, the most appropriate targets for vaccine and drug development.
If CD134 CRD2-dependent infection is a signature of FIV isolates from the 'early' stage of infection, such 'early' virus strains would appear to be the most appropriate targets for vaccine development.
As the process of lytic virus replication is effective at destroying injected tumours, the most appropriate targets for RNAi-mediated knockdown using this approach would be expected to be secreted tumour proteins involved in processes such as angiogenesis or local immune suppression.
Similar(52)
The success of a targeted therapeutic depends not only on the identification of the most appropriate target but also on how it is combined with other targeted drugs.
HOM identifies the most appropriate target eNodeB the UE should be handed over to.
After over 7 months of effort, T bank identified the most appropriate target and completed their first investment in 2016.
Determining the most appropriate targeting strategy and delivery mechanism requires organizational capacity to understand the context, foresee potential risks, and design assistance in a way that effectively mitigates risks.
Therefore, diagnostic tools to identify the most appropriate target manipulated for the treatment should be developed.
More suggestions(15)
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most basic targets
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most sensitive targets
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com