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Hence, the HER2 status is not considered a selection criterion for the most appropriate endocrine treatment.
Pharmacologic and clinical differences exist between third-generation inhibitors and should be considered in the selection of the most appropriate endocrine therapy [ 64, 77].
The final results are expected to be released in 2008 [ 51], but until then, the most appropriate endocrine therapy will need to be selected on the basis of currently available evidence.
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This latter approach is now considered the most appropriate approach for most endocrine-related diseases/disorders (U.S. Environmental Protection Agency 2012).
The present research therefore aims to determine whether peak nutrient flux into the blood plasma is the most appropriate time point to investigate the endocrine regulation of growth and appetite under conditions of normal and high temperature, and to investigate the interrelationship between appetite and growth on a pre- and post-prandial time scale.
We conclude that in vivo studies are most appropriate for testing an organism's integrated endocrine response to nitrate.
When nsAI treatment fails, it is unclear which endocrine therapy is the most appropriate.
When AI treatment fails, it is unclear which endocrine therapy is the most appropriate.
Unfortunately, the majority of patients treated with AIs eventually develop resistance to these drugs [ 6] and when resistance occurs it is unclear which endocrine therapy is the most appropriate.
After the failure of a non-steroidal aromatase inhibitor (nsAI) for postmenopausal patients with metastatic breast cancer (mBC), it is unclear which of various kinds of endocrine therapy is the most appropriate.
Though MRI now has an established place in the diagnosis of breast cancer, it is becoming clear that it can directly affect surgical and medical management by enabling assessment of response to chemotherapy and endocrine therapy, and facilitating choice of the most appropriate surgery.
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