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6 In both cases we compared each intervention group with the most appropriate comparator group as shown in table 1. Massage=Six sessions of therapeutic massage, one session per week.
While specific reasons for the downward trend are difficult to isolate, the trend supports using early (first 6 months) rates from the cohort as the most appropriate comparator for STARHS-based estimates.
Gliclazide was selected as the most appropriate comparator because of its lower risk of hypoglycaemia.
43 It is for this reason that our primary comparator group consisted of sulfonylurea users, which we believe is the clinically most appropriate comparator.
We believe the reviews of bench research serve as the most appropriate comparator for examining quality of reviews of animal research as both belong to the basic biomedical research domain.
However, during the study period the GLF was the largest survey providing regional prevalence data for Great Britain, and we believe that this is therefore the most appropriate comparator.
Similar(50)
As the appropriate comparator is most often the cheapest available product (i.e. generic or reference price) it has to be assumed that cost containment is one of the main drivers for the decision.
Contrasting results when comparing SGLT2 inhibitor initiators to DPP-4 inhibitor and SU initiators highlight the importance of choosing appropriate comparator drugs when addressing comparative effectiveness and safety questions that can inform clinical decision-making.
So any information on costs and cost-effectiveness compared with an appropriate comparator will be presented.
Randomisation is essential for a comparison of safety among those receiving a study intervention compared to an appropriate comparator group.
Considering this, and taking into account that pemetrexed is only indicated in nonsquamous patients, whereas most EGFR wild-type patients are squamous, we did not regard pemetrexed as an appropriate comparator and therefore focused our analysis on comparing erlotinib with best supportive care.
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