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The most apparent defect in Cavin-3 KO animals is cachexia as evidenced by a 40% reduction in weight and severe lipodystrophy.
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3) The most apparent early defect observed in M ybx1 mutants is that of mRNA transport along what appear to be axial streamers, from the ooplasm in the yolk to the blastodisc where the mRNA becomes localized.
The primary and most readily apparent defect in mice with ablation of Esrp1 alone was fully penetrant bilateral cleft lip and palate (CL/P).
This was most apparent at the defect edge, where a thin layer of osteoid was apparent on the ectocranial surface (middle columns, Figure 4A).
A region of interest with width of 120 pixels and height of 150 pixels is truncated from the selected slice showing the sectioning of the right and left atria, where the septal defect is most apparent.
The specific nature of the defect was most apparent for the shorter truncation Cik11 521 Kar3, which was able to bind microtubules under our standard conditions, but instead of smooth translocation it displayed erratic forward and backward displacements that did not lead to directional movement as revealed by kymographs.
Instead, their mutant defects became most apparent during pollen germination and, in the case of eif3h, pollen tube growth.
CT images revealed sacralization of L5 and the most caudal lumbar vertebra was present at L4, and an apparent defect in the L4 lamina was thought to be bilateral intralaminar laminolysis (Fig. 4a, b).
Our results confirm that a structural defect in collagen IV can lead to the loss of BM, which is probably most apparent in tissues such as tendon that are under considerable mechanical wear-and-tear.
This is most apparent in fiscal policy.
Most apparent on the gorgeous Glass Eyes.
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