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Pro-apoptotic BH3-only proteins are the most apical mediators of cell death and their pro-apoptotic activity is tightly regulated by diverse transcriptional and post-transcriptional mechanisms (Puthalakath and Strasser, 2002).
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Note the presence of "pseudo diverticulum" in the most apical myocardium (arrowhead).
Tight junctions are the most apical organelle of the apical junctional complex and are primarily involved in the regulation of paracellular permeability and membrane polarity.
Psychophysical experiments were conduced to measure rate discrimination in individual electrodes from the most apical to the most basal electrodes.
With pulpal necrosis, bacteria and their byproducts, as well as infected dentinal debris may remain in the most apical portion of the canal; these irritants may jeopardize apical healing.
Middle resorptions were measured from the most cervical resorption point to the most apical resorption point in a linear line (Fig. 3, score 6).
In contrast, closure of the most apical septum was generally slower.
Wildtype choroid plexus cells exhibited a distinctive polarization with an apical, centriolar zone (CZ, Figure 4A) above a separate zone of mitochondria (MZ, Figure 4A); the most apical mitochondria were found an average of 7 µm from the apical surface.
Only the most apical regions of wild-type epithelia showed small patches of extra outer hair cells (Fig. 5B′′).
In addition, the differences are generally concentrated in the deepest nodes, rather than the most apical ones.
Epithelial downgrowth was measured from the gingival margin to the most apical extent of the junctional epithelium (Fig. 2b ).
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