Sentence examples for most altered pathways from inspiring English sources

Most altered pathways were not significantly different between SAPSII-high and SAPSII-low groups of patients.

Finally, we remark that the transcriptogram analysis provides a hierarchical assessment of gene expression data, starting from a global view of the metabolic differences, then indicating the most altered pathways, and finally pointing to the genes participating in these alterations, as provided by the files in supplementary materials online.

The PI3K pathway is now recognized to be one of the most altered pathways in human breast cancer.

The phosphatidylinositol 3-kinase (PI3K) pathway, a key mediator of GFR signaling, is one of the most altered pathways in breast cancer.

ERK and PI3K/AKT have been identified as the two most commonly altered pathways in prostate cancer with alteration frequency of 42 43 % in primary and 90 100 % in metastatic prostate cancer [ 148].

The JAK/STAT pathway is one of the most frequently altered pathways in HL.

Deregulation of the PI3K/PTEN/AKT pathway is one of the most common altered pathways in human malignancy.

A recent systematic characterization of somatic mutations in 441 human tumors identified growth factor receptor signaling to MEK1/2-ERK pathway to be one of the most significantly altered pathways across human cancers [33].

Manual curation was conducted for the most significantly altered pathways to ensure accuracy.

The most significantly altered pathways are involved in cell cycle regulation and DNA replication.

Surprisingly, all the most significantly altered pathways, including 7 upregulated and 5 downregulated pathways, are metabolic pathways.