Sentence examples for most aggressive subgroup from inspiring English sources
Hence we focused our efforts on the second most aggressive subgroup, which was subgroup #1.
BCL-6 was found to be overexpressed in breast cancer [ 22] and in 68% of histological high-grade ductal breast cancers, clinically the most aggressive subgroup of breast cancer.
We sought to identify compounds with subgroup specificity for the most aggressive subgroups based on our analyses of DMFS in the patient cohorts.
DOI: 10.1038/sj/bjc/6600130 www.bjcancer.com © 2002 Cancer Research UK Small cell lung cancer (SCLC) represents one of the most aggressive subgroups of lung cancer, and, despite its initial sensitivity to chemotherapy, most patients with this type of cancer die of metastatic disease in less than 2 years from diagnosis (Brigham et al, 1978).
The most common and aggressive subgroup, posterior fossa ependymoma group A (PF-EPN-A), occurs in young children and appears to lack recurrent somatic mutations.
The most aggressive of four medulloblastoma (MB) subgroups are cMyc-driven group 3 (G3) tumors, some of which overexpress EZH2, the histone H3K27 mono-, di-, and trimethylase of polycomb-repressive complex 2. Ezhashas a context-dependent role in different cancers as an oncogene or tumor suppressor and retards tumor progression in a mouse model of G3 MB.
Basal-like carcinomas (BLCs) and human epidermal growth factor receptor 2 overexpressing (HER2+) carcinomas are the subgroups of breast cancers that have the most aggressive clinical behaviour.
Although some molecular subgroups of breast cancer have a targeted therapy, the most aggressive tumours still lack a molecular target.
Although some molecular subgroups of breast cancer are beneficed from a targeted therapy, the most aggressive tumors still lack molecular targets, representing a clinical challenge.
America's most aggressive chief executive?
