Sentence examples for most aggressive phenotypes from inspiring English sources

The results of male-male aggressive interactions, while largely transitive, in some cases strongly depart from the expectation population-mean values leads us to expect, particularly for.the most aggressive phenotypes.

On the other hand, increased expression of Cat X was found in both tumour and immune cells of prostate [ 22] and gastric cancer [ 17] and in the most aggressive phenotypes of malignant melanoma [ 23].

This finding complements the data shown in Figure1A and B where WI-38THP-2 presenthe the most aggressive phenotype and a milder phenotype was presented in WI-38THP-1.

The extremely rare S52P TTR variant is the least stable TTR variant and causes the most aggressive phenotype of hereditary systemic TTR amyloidosis (Mangione et al, 2014).

The KRAS/LKB1 double knockout was in fact the most aggressive phenotype of all tumours considered in the study, and had an additional feature that had not previously been reported in a mouse model: squamous cell carcinoma histology.

In contrast, inflammatory carcinomas appear to have the most aggressive phenotype of any of the histologic types evaluated as these tumours were more likely to be node positive, to be hormone receptor negative, and to have a high grade.

These data validate in vivo our previous assumption on GBM CSC distribution, showing that core cells in the GBM mass contain the highest amount of CSCs and display the most aggressive phenotype.

Importantly, although HIF-1α is thought to contribute to tumor aggressiveness, 38, 39 reoxygenated Ch-H-R cells, which have the lowest ratio of HIF-1α positive cells among Ac-H cells, Ch-H-R cells and reoxygenated Ch-H-R cells, showed the most aggressive phenotype among these three types of cells (Fig. 1b,c).

An alternative interpretation is that poor oxygenation is a secondary effect of tumour aggressiveness, i.e. the most aggressive cell phenotypes develop the most hypoxic primary tumours.

Our intention therefore is not to suggest that RBM47 has specific functions suppressing metastasis, but rather that its loss contributes to the establishment of the most aggressive cancer phenotypes that are vital to metastatic dissemination.

Crescentic glomerulonephritis (CGN) is the most aggressive structural phenotype in the continuum of injury that results from glomerular inflammation.