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The two hystotypes display significant biological and clinical differences: PTC is a well differentiated form of tumour with a high incidence and a good prognosis, while the ATC is less frequent but represents one of the most aggressive endocrine tumours with morphological features of an undifferentiated type.
ATC is one of the most aggressive endocrine tumors characterized by high degree of dedifferentiation [1].
Anaplastic thyroid carcinoma (ATC) is one of the most aggressive endocrine tumors with morphological features of undifferentiated neoplasm.
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