Sentence examples for most aggressive disease from inspiring English sources

MYCN amplified neuroblastoma is the most aggressive disease subtype.

In our Drosophila model, muscles expressing the DVAP-V260I transgene, which associates with the most aggressive disease phenotype, exhibit a relocalization of DVAP protein into the nucleus.

Interestingly, all patients (5/31 tested) with histological staining for cyclin D1 were classified into group A, which included those with the most aggressive disease.

Indeed, leukemia patients with p53 deficiency represent a group with a high resistance to radio- and chemotherapy and demonstrate the most aggressive disease courses.

Molecular signatures associated with the most aggressive disease will provide a rationale for early adjuvant treatment immediately after prostatectomy, or indeed after initial biopsy when such technologies can be applied to an 18 mm core biopsy.

Accounting for the contribution of tumour proliferation in our CAIX-based prognostic assay (Brockton et al, 2012), by stratifying patients based on tumour ki67 status (Ki67losCAIXhi), identified patients with the most aggressive disease course.

Cadmium and arsenic as xenoestrogens may also induce kidney cancer [ 94, 95] Understanding of pancreatic cancer aetiology is crucial, as it is the fourth leading cause of cancer deaths in the USA [ 64] and one of the most aggressive diseases.

Adenocarcinoma of the pancreas is one of the most aggressive cancer diseases affecting the human body.

SARS-CoV is the most aggressive, although the disease seems to be substantially less severe in children than in adults.

Finally, it is theoretically possible that a neoadjuvant approach will "weed out" the patients with the most aggressive, treatment-resistant disease.

The association of CD44 with the most aggressive subtype of disease is consistent with the well-established cellular functions of CD44 in promoting cell invasion and cell adhesion in vitro, and the capacity for CD44 to increase spontaneous metastasis of breast cancer cells in vivo [7,8; McFarlane S, Coulter J, Waugh DJJ, unpublished observations].