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Without treatment, most patients live fewer than 3 months; with the most aggressive combination therapies, the median survival is still less than 20 months.
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Regardless of the mechanisms of resistance, most solid malignant tumors have a cell population, which survives the most aggressive combinations of highly cytotoxic drugs given on a variety of schedules.
Those diagnosed over 1 year of age have a less favourable outlook and often fail to respond even to the most aggressive combinations of therapy.
Somehow, that most aggressive flavor combination mellows and softens and becomes a subtle complement to the earthy flavor of the potatoes.
Finally, it also misses the chance to take seriously his strange late work, the paintings of men, women and alpine landscapes that have some of the most aggressive color combinations before Op Art.
Our primary objective was to identify prognostic factors for DFS, which might help better defining node-negative BC patients candidate to the most aggressive and costly anthracycline/taxane combinations.
The most aggressive of the 4 treatment combinations (TEH plus TBH) had a CA estimate 20% smaller than for the most gentle treatment combination (TEL plus TBL).
It's truly strange, and it presents evidence that Skrillex is digging for new combinations without neglecting his basest, most aggressive tendencies. .
OCIP23, which is the most aggressive growing model, showed the best response to the RDEA119 single agent or the combination treatment.
Of all combinations analysed, cells expressing both HER1 and HER2 were the most aggressive (Cohen et al, 1996).
For all cell combination experiments, fibroblasts were used at a 2.5:1 ratio to promote the most aggressive behavior of epithelial cells (data not shown).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com