Sentence examples for most aggressive cells from inspiring English sources

The author observed that the Mn induced a longitudinal relaxation rate (R1) in the most aggressive cells significantly higher (two times) than that in less aggressive ones.

Nevertheless, the authors found that the most aggressive cells that showed the lowest level of CaSR expression enhanced the most markedly whereas the less aggressive cells with higher levels of CaSR expression enhanced only minimally; furthermore, the higher the concentration of MnCl2 administration, the greater the enhancement of both cells.

The morphology and the number of nucleoli is very different in the most aggressive cells compared with the MP control cells.

As shown in Fig. 6C, ribosomes of both cell lines displayed the ability to pass through the premature stop codon although this dysfunctional property was 30% higher in the most aggressive cells MA- cells than the control cells MP.

Because ribosome biogenesis is a complex multistep process and because the post-transcriptional modifications of the rRNA are crucial for ribosomal functions, the next step of the study was to determine whether these steps of ribosome biogenesis were also modified in the most aggressive cells (MA-) compared to the less aggressive cells (MP).

Respective fold changes of the rate of methylation between MA- and MP cells for the three sites analyzed were 1.8, 1.6 and 1.1 with the RT-qPCR method and 1.35, 1.85 and 1.06 with the standard method.These results confirmed that the rate of rRNA methylation of at least some sites is higher in the most aggressive cells.

An alternative interpretation is that poor oxygenation is a secondary effect of tumour aggressiveness, i.e. the most aggressive cell phenotypes develop the most hypoxic primary tumours.

In various cervical cancer cell lines known to exhibit different degrees of aggressivity, the highest levels of colony stimulating factor are found in the most aggressive cell lines (Bretscher et al, 2000).

This unambiguously showed that the rate of ribosome synthesis is higher in the most aggressive cell line, MA-.

The ratio between the MR of the two cell line are presented in figure 4C, and we can show that this ratio is between 1.4 and 6 fold higher for the most aggressive cell.

Similarly, the TGF-β receptors, TβRI and TβRII, were highly expressed in the most aggressive cell line Hs578T (p < 0.001 and p < 0.05, respectively).