Sentence examples for most aggressive breast from inspiring English sources

A type of breast cancer in cats has been associated with the same protein HER2 as one of the most aggressive breast cancers in women, and the bone cancer osteosarcoma is nearly identical both clinically and genetically in dogs and people.

But for some women it's an unavoidable eventuality: with the most aggressive breast cancer tumours, removal of tissue or the entire breast is a necessity. .

However, as the most aggressive breast cancers may stably exhibit a mesenchymal phenotype, it is conceivable that distant metastasis might also relate to the mesenchymal phenotype.

The results shown above demonstrated that the combination of our A17 signatures are intrinsically effective in identifying the most aggressive breast tumors (basal-like) and bone metastasis, in predicting clinical outcome and in characterizing changes associated to hormonal therapy-resistance in ER-positive breast tumors.

Reduced ATM expression within malignant breast epithelial tissues was predominant in HNBC, especially TNBC, the most aggressive breast cancer type.

16 Moreover, basal type breast cancer cells have been known as the most aggressive breast cancer type.

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Decreased or absent tumor cell XOR has been observed in the most aggressive human breast cancer[129], gastric cancer[130], colorectal cancer[131], ovarian cancer[132], non-small-cell lung cancer[133], and in rat hepatic cancer[134, 135].

Furthermore, microarrays show that increased PrP mRNA levels are associated with ER stress in the most aggressive basal breast carcinoma cell lines compared with the less aggressive luminal cell lines ([ 55] and Figure 1).

Approximately 30 40% of breast cancers are estrogen receptor (ER) negative and the triple negative breast cancer (TNBC i.e. negative for ERα, PR and Her2 amplification) are the most clinically aggressive breast tumors [1], [2].

We are very enthusiastic about this finding, and believe that our work will have enormous impact on guiding the development of therapy for basal-like breast cancer, the most aggressive subtype of breast cancer lacking any proven targeted therapy.