Sentence examples for most affected tissues from inspiring English sources

However, the scientists behind the research believe that the new approach now opens the way to developing stem-cell treatments that restore the energy supply to the most affected tissues, leading to new therapies and possibly even cures.

Intraoral hemangioma appears in the head and neck area unfrequently, but oral mucosa and skin are the most affected tissues in the oral cavity followed by the surrounding bone and muscle.

Numerous studies have demonstrated the potential nature of relevant biomarkers in the spinal cord, which is one of the most affected tissues.

Clam gills were used because they are the main connection with the outside environment, together with the siphons which are one of the most affected tissues upon Perkinsus parasitism [ 36].

Although defects were also noticed in the intestinal wall as well as in other tissues such as heart and pancreas, the gut epithelium was by far, the most affected tissues in RT2OcKO mice.

In particular, it is plausible that the loss/decrease of plasticity and/or onset of self-renewal defects in mesenchymal stem cells may be responsible for the specificity of accelerated tissue degeneration, as most affected tissues in progeria are of mesenchymal origin [18].

Such mtDNA copy number increase was not paralleled by an augmentation of mitochondrial mass in some investigated tissues, predominantly in the most affected tissue regions of the brain.

C4BP positivity extends beyond the area positive for C3b, which suggests that C4BP is a functional complement inhibitor in AMI and limits complement activation to the most affected tissue.

CUG foci have been most extensively studied in skeletal muscle, which is the most affected tissue in individuals with DM1 (12 120 20, 30).

The relative abundance of the transcripts in brain from MLD patients was substantially higher than that observed in T lymphocytes, suggesting that increased expression of MTs could be directly linked to disease pathogenesis in the most affected tissue.

However, we cannot exclude that altered mechanisms downstream of the collagen VI deficiency may interfere with the correct α6 chain production selectively in the skeletal muscle, the most affected tissue in collagen VI-related patients.