Sentence examples for most affected mutants from inspiring English sources

It is important to note that chemotaxis and motility mutants are among the most affected mutants in competitive rhizosphere colonization [ 44, 53] and that the rhizospheric environment selects for hypermotile phenotypic variants [ 14, 54] that are frequently hypercompetitive [ 14].

The residues - R807 and K646, reported to be the most affected mutants, are also predicted by ABS-Scan to be essential, with the highest predicted ∆∆G score of 3.63 and 3.39 respectively.

The bub1 and mad1 cells were the most affected mutants (p < 0.001), whilst the growth rate of the tel1 cells was augmented compared to the growth rate of wild type at day 21 and day 28 of chronological culture (p < 0.001) (Fig. S1).

The AUG S1+2+3 KO virus was the most affected mutant virus, with a 3-log reduction in virus production compared to the WT virus.

Thus, a SV40 TAg NLS was inserted at the C-terminus of either wt or each of the most affected PB2 mutants, KNRQ, 8/K and ΔNLS (see Fig. 4A for a diagram), and the localisations of the chimeric proteins were tested by indirect immunofluorescence of transfected cells.

PD-1-deficiency leads to the highest MBP loss in the myelin mutants and the most seriously affected mutants belong to the PD-1-deficient group.

Mobility shift of Cdc24CDK-A/PAK-A in the double mutants was identical to that in the most affected single mutant, ruling out a synthetic effect on phosphorylation (Figure 4).

fruC mutants were the most affected, and fruA mutants the least.

We therefore conclude that Dbx1-derived cells do not massively contribute to some of the territories that are most affected in ablated mutants, namely the forebrain and face, suggesting that the defects observed are non cell-autonomous.

To determine whether the spatiotemporal expression pattern of creb3l2 during development matches the structures that are most affected in feelgood mutants, we analyzed RNA samples by reverse transcriptase (RT -PCR and embRT -PCR whole mount in situ hybridizandon at sembryosal developmental time points.

We showed that susceptibility to bilirubin damage and, consequently, survival of mutant animals is strain-specific, with a significant increase in the survival of FVB/NJ- Ugt1−/− compared with C57BL/6- Ugt1−/− mice, the cerebellum being the most affected organ in both mutant strains.