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Ankles were the most affected joints.
So far, mostly small joints such as the MCP-, PIP-, MTP-joints and wrists were enrolled into the scanning protocols, being the most affected joints in RA.
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The elbow (specifically the capitulum of the humerus) is the second most affected joint with 6% of cases; the talar dome of the ankle represents 4% of cases.
Therein, MTP-2 was the single most affected joint.
Seventy-one persons (59.7%) reported that the main affection of OA was the knee(s), while 48 (40.3%) reported hip(s) as the most affected joint.
Despite all the benefits of recreational running, musculoskeletal injuries are frequent in runners with a reported prevalence of up to 79%%, the knee being the most affected joint.
Wrist being the most affected joint in RA (mean of 67% of cases), it has been selected as a" target joint" in clinical trials, being used in most of the scores available to date.
For each flare, patients recorded in a diary the start date, the most affected joint on that day and the severity of pain (see supplementary material for further details).
As recently published for RA [ 6], the most affected large joint was sonographically examined in a standardized modified manner according to the German [ 9] and European League against Rheumatism (EULAR) [ 10] guidelines at baseline and the follow up visits.
They report uptake in most of the affected joints, starting within minutes after injection and persisting at 24 h.
MRI of the clinically most affected knee (target joint) was performed.
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