Sentence examples for most affected category from inspiring English sources
The regulation of a small number of genes could be attributed to the specific effect of ECO (311 features) with metabolism being the most affected category.
For instance, in contrast to neural stem cells, we did not detect intron-retention events as one of the most affected category and we reasoned that these differences could be explained by transcriptomic differences among distinct cell types.
Conclusion: Acute poisoning remains high and steady in the Oran region and the under-25 age group represents the most affected category.
Amino acid metabolism was the second most affected category with 19 repressed and 20 induced genes.
The second most affected category included genes involved in "stress response".
Similarly, as in the baseline study, the most affected category was Recreation and pastimes with a mean (SD) SIP score of 13 (16; table 3).
In a previous comparative microarray analysis we defined a set of 361 genes that showed at least a 2-fold statistically significant alteration in HGPS compared to normal controls; extracellular matrix proteins and transcription factors were the most affected categories, with growth-arrest specific transcription factor MEOX2/GAX being the most significantly affected gene [ 5].
Functional analysis of the gene expression data showed that nervous system development and function were the most affected categories in the "high lead" group (Table 5).
Here, all genes included in the most affected categories 'metabolism' and 'structural modification', identified by the GO enrichment analysis, were considered.
Sequence annotation and classification according to Gene Ontology categories [ 23], revealed that at both time points primary (mainly signal transduction related genes) and secondary metabolisms, together with response to the stimulus, were the most affected categories (Additional Files 3 and 4).
Functional category analysis of the induced genes showed that the most affected functional categories were "hypothetical proteins", representing a total of more than 40% of all the up-regulated genes, consistent with the fact that nearly half of the genes in the Synechocystis genome are still annotated as hypothetical up to now [ 27].
