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The most actively expressed nifH sequences were not the most prevalent in the DNA samples.
Alternate splicing results in isoforms of various lengths, the most actively expressed in humans being VEGF121, VEGF165, and VEGF189.
These metagenes also represent the most actively expressed metagenes our analysis uncovered.
Moreover, the top 20 domains revealed the most actively expressed gene families in the onion (Fig. 4A).
In the correlation network of Figure 5, metagene 1 is comprised of genes which are the most actively expressed across all samples within the dataset.
The WWOX gene encompasses FRA16D, the second most actively expressed FS in humans and a region prone to breakage with an increased risk for carcinogen-induced damage (Popescu, 2003; Ludes-Meyers et al, 2003).
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Consistent with previous comparative results (Nanty et al. 2011; H unt et al. 2013b), the hPTMs that are generally most strongly associated with actively expressed genes (H3K4me3, H3K27ac, and H3K36me3; Kharchenko et al. 2011) were highly overrepresented among methylated genes.
There are several other genes in C. beijerinckii 8052 annotated as motility-related, although most of them are not actively expressed during the fermentation process.
Interestingly, our results also suggest that most HeT-A copies are actively expressed regardless of which telomere and where in the telomere they are located.
On the other hand, telomerase is actively expressed in most high-grade astrocytomas and embryonal brain tumours (Falchetti et al, 2002; Hakin-Smith et al, 2003), which may contribute to their worse outcome.
Genes directly targeted by MYC have been identified in various tumors [ 8, 9], but more recent studies suggest that this oncogene might be a "universal amplifier" with effects on most of the cell's actively expressed genes.
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