Sentence examples for most active pathway from inspiring English sources

NAMPT catalyzes the rate-limiting step of the most active pathway of NAD+ synthesis.

Nicotinamide phosphoribosyltransferase (NAMPT) inhibitors (e.g., FK866) target the most active pathway of NAD+ synthesis in tumor cells, but lack tumor-selectivity for use as a single agent.

Each exhaustive search resulted in a listing of the 10 most active pathways, based on the gene expression data of the microarray and the corresponding network.

The lipid metabolism pathway in anhydrobiotes is one of the most active pathways as lipids are the main reservoir of energy and the most likely source of carbon for the synthesis of trehalose [ 21].

Finally, we run CellFateScout over all pathways (chains) in the network starting with a small molecule target gene, and for each small molecule, the 100 most active pathways along with their p-values are stored in the SMMD.

Our results present a first transcriptome sequencing and de novo assembly for a lichen species and describe the ongoing molecular processes and the most active pathways in C. rangiferina.

Glycolysis is in every circumstance the most active metabolic pathway denoting the "Warburg" like metabolic behavior that characterizes many cancer cells.

We have obtained a basic view of the ongoing molecular processes and have identified the most active biological pathways in C. rangiferina.

After computation, the most active signaling pathways with lowest p-values in the input Cytoscape network are shown in a table and marked by colors in the table and the Cytoscape network view.

Thus, our study is in accordance with Hayashi et al. [ 25] because the Nod factors perception cause metabolic changes, and here we can observed that the metabolic pathways most active in the presence of rhizobia were glycolysis and the Krebs cycle (Additional file 2: Figures S1 and S2).

Preliminary studies of the mechanism of action revealed that the most active compound exerts its activity through ERK1/2 signaling pathway activation, especially on DA neurons.