Sentence examples for most active lead from inspiring English sources

Most of the tested compounds were proved to be effective in inhibiting HIV-1 (IIIB) replication with EC50 ranging from 0.15 μM to 24.2 μM, thereinto compound 15 was the most active lead with favorable inhibitory activity against HIV-1 (IIIB) (EC50 = 0.15 μM, SI = 684).

In the chart below, you can find a list of the most active lead investors, globally, across all stages.

Where, a training set representing the most active lead analogs [12, 13] was selected, energy minimized and submitted to flexible alignment for analyzing the shared spatial arrangement of their pharmacophoric features.

Based on the results of reducing power assay 1-[1- 2,4-dihydroxyphenyl -3- 2-hydroxyphenyl)allylidene]-4-(4-methylphenyl)semicarbazide (compound 1-[1- 2,4-dihydroxyphenyl -3- 2-hydroxyphenylxyphenyl)allylidene]-4-(4-methylphenyl)semicarbazide (compound 21-[1- 2,4-dihydroxyphenyl -3- 2-hydroxyphenyl

These compounds were tested for their biological activity; the compound 22 emerged as the most active potent lead with an IC50 of 3.2 ± 0.15 μM against Mycobacterium smegmatis DNA gyraseB enzyme and 0.81 ± 0.24 μM in MTB supercoiling activity.

Silicon Valley-based venture firms also rank as the most active global lead investors.

The explanation is probably that most active fixation leads are isodiametric, at least pacing ones.

A further research on most active synthesized compounds as lead molecules may result in discovery of novel anticancer and antitubercular agents.

Therefore, we have used an in vitro plaque assay to screen a limited proprietary library of small organic compounds and identified highly bioactive leads, with the most active analogs showing activity in low picomolar range.

The adoption of midazolam as an alternative drug - not only in Ohio, but also in Florida, one of the most active death penalty states – has led to expressions of anger and disgust by leading physicians in the US.

The two most active CVC investors, Google Ventures and Intel Capital, have led the pack since 2011.