Sentence examples for most active inhibitor from inspiring English sources

5d, 5e, 5f, 5g, 5i, and 5l show better activity and the most active inhibitor of tuberculosis 5f showed a promising inhibition of M. tuberculosis with MIC value of 16 μg/mL.

This effort afforded the most active inhibitor 13f with improved activity in not only target-based level, but also cell-based level compared with the original hit 1.

Compound 1l was the most active inhibitor in this series with an IC50 of 0.22 μM.

Compound 3sf was revealed as the most active inhibitor in this series with an IC50 of 0.029 μM.

The most active inhibitor against BuChE was 4b with IC50 value of 0.51 ± 0.01 μM, which bears prenyl substituted in the position 3.

The binding affinities of the most active inhibitor of these T6PP orthologs, 4-n-octylphenyl α-d-glucopyranoside 6-sulfate (9a), were found to be in the low micromolar range.

The most active inhibitors exhibited potent in vitro activity with low micromolar IC50 values in anti-proliferation and Her2 degradation assays.

One of the most active inhibitors, compound 20 exhibited stronger in vitro cholesterol absorption activity than ezetimibe, no cytotoxicity in HEK293 and RAW264.7 cell lines and satisfied lipophilicity.

The positive charge/LUMO of most active inhibitors is localized on the central Arg residue of the required triplet.

The most active inhibitors combined a mercapto group and a phosphonate ester or acid, with two/three carbon chains connecting a phenyl group.

Binding mode analysis of the most active inhibitors showed that these are well accommodated into the binding site of enzyme though stable hydrogen bonding and hydrophobic interactions.