Exact(3)
While Alu and SVA are the most active elements in the human genome, L1 is the real culprit, since it encodes the enzymatic machinery that the SINEs exploit.
However, such analyses have some limitations because, although it may identify most active elements, other functional TEs can be missed due to their low transposition frequency.
Two of the most active elements, the Chr 3 and Chr 14 elements, are L1s absent from the reference but present respectively in 77 % and 25%% of cases examined by Tubio et al. [ 13].
Similar(57)
This is in contrast to the initial analysis of the mouse genome sequence in which LINEs appeared to be the most active element, with LTRs and SINEs showing similar levels of activity [21].
NP is the most active element of the physiological hydrodynamical system of the intervertebral disc extradiscal space [ 56].
These data demonstrate that most active regulatory elements were located within 1 kb from the upstream of TSS region, and some repression elements were located between 3 kb and 4 kb from upstream of the TSS region.
If we take the present number of LTR copies to be an indicator of former transpositional activity, the Ty1 elements can be said to be the most transpositionally active elements in the S. cerevisiae species as a whole.
The human ERV-K (HERV-K) family includes some of the most active retroviral elements in human genome [6], [7].
The LTR subfamilies were the most active retrotransposable elements, with a general trend towards increased polymerase binding in transformed cells.
This enrichment of breakpoint regions in specific TE families may be due (1) to the fact that these TE families were among the most transpositionally active elements in the D. buzzatii genome when the opportunity window for insertion was open, and/or (2) to insertional preference [83].
The chicken repeat 1 retroposon (CR1) family belongs to LINEs (Stumph et al. 1981; Burch et al. 1993; Suh et al. 2014) and represents the most active transposable element in avian genomes, for example, it accounts for ∼85% of all transposable elements in chicken (Hillier et al. 2004).
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