Sentence examples for most active anticancer from inspiring English sources

In this study, compound b31 was found to be most active anticancer one (Table 27, Fig. 7) [35].

Table 20 Antitumor potential results of compounds b13 and b14 Compounds Human leukaemia (HL-60) cancer cell IC50 = µmol/l b13 0.08 b14 0.21 Doxorubicin 0.55 Fig. 6 Chemical structures of the most active anticancer pyrimidine derivatives (b13 b23).

Evaluation of the synthesized compounds against HEPG2 hepatocellular carcinoma cells in vitro identified compounds 5b, 6b and 10 13b as most active anticancer agents with IC50 equal to 0.12, 0.29, 0.58, 0.44, 0.42 and 0.66 µM, respectively.

Table 24 Anticancer activity results of b24 and b25 Compounds Cytotoxicity (IC50 in nM) NUGC DLDI HA22T HONEI HONEI MCF WI38 b24 180 740 234 837 644 269 Na b25 40 64 82 328 260 173 Na CHS 828 25 2315 2067 1245 15 18 Na Fig. 7 Chemical structures of the most active anticancer pyrimidine derivatives (b24 b32).

Doxorubicin is among the most active anticancer agents widely used in treatment of solid tumors and leukemia [ 1] with cytotoxic, cytostatic, and antineoplastic effects.

Irinotecan (CPT 11) was selected also because it is one of the most active anticancer agent in colon cancer (Rougier et al, 1998).

Doxorubicin is one of the most widely used and active anticancer agents.

The most active analog 20 showed potent in vitro anticancer activity against the MDA-MB-231 breast cancer cells at low μM concentrations, with minimal toxicity on the non-tumorigenic MCF-10A mammary epithelial cells.

Also the most active compound 6 showed its activity on potentiation of anticancer agents, temozolamide and etoposide, by 1.7 times, respectively.

The current study has widened the scope of developing the most active bis-pyrimidine molecules as promising antimicrobial and anticancer agents.

Ovarian cancer is in many cases a chronic disease characterised by protracted sensitivity to anticancer agents, of which the most active are the platinum coordination complexes.