Sentence examples for most abundant codons from inspiring English sources

The most abundant codons are preferred because of the abundance of the cognate tRNAs [ 5- 9], and thus the use of the codons maximizes the translation speed and minimizes the amino acid misincorporation rate [ 3, 10].

The measure is the previously studied codon adaptation index, which favors the use, in the gene to be optimized, of the most abundant codons found in the host genome.

OptZGP was further codon optimized to 70% by choosing the most abundant and/or second most abundant codons.

A synthetic gene encoding the same protein sequence as described above for the LSA-NRCH was designed based on using the most abundant codons associated with highly expressed proteins in E. coli [46].

The anticodon of 21 tRNA genes (out of a total of 22), regardless of which strand they are located, have anticodons with their wobble site forming Watson-Crick base-paring with the most abundant codons in each codon family, i.e., the wobble site of the tRNA genes is either a U to pair with the abundant A-ending codons or a G to pair with the abundant C-ending codons [17].

Among them, the three most abundant codons in both mitogenomes are UUA [Leu (UUR ], AUU (Ile), and UUU (Phe).

In addition, analysis of the entire Boi transcript data set and assessment of codon abundance shows that the conserved codon is often not the most abundant codon in the transcript library.

As observed by others (e.g., [ 20]), there was no self-evident link between abundance of codon families and the level of tRNA conservation, with the most abundant codon families (Leu2, Ile and Phe) not having the highest %INUCs (see below).

In other words, the tRNA anticodon should evolve to match the most abundant codon in a synonymous codon family.

The codon-anticodon adaptation hypothesis [17] [20], [23], [26] predicts that the anticodon should match the most abundant codon.

The codon-anticodon adaptation is long known [18] [23], and the pattern described above would have been nice but boring had there not been an interesting and singular exception to the general pattern of tRNA anticodon matching the most abundant codon.