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If millions of mosquitoes were released, even that small percentage of females could lead to a temporary increase in disease spread.
Company spokeswoman Chris Creese said the test will be similar in size to Oxitec's 2012 experiment in the Cayman Islands, where 3.3 million modified mosquitoes were released over six months, suppressing 96% of the targeted bugs.
Then mosquitoes were released.
There, some 3 million mosquitoes were released to test whether they could actually help bring down the local population.
About a year ago, genetically modified (GM) mosquitoes were released into the wild and they have been flying under the world's radar screen until last week.
For these trials, mosquitoes were released over smaller areas reaching only thousands of residents.
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"We would want to ensure that the risks are properly considered before GM mosquitoes are released into the environment.
"Will Oxitec be required to obtain the free and informed consent of Key West residents?" On his Friends of the Earth blog, Hoffman also asked what happens when female mosquitoes are released along with the males and what happens when the young mosquitoes do not do what they were modified to do – die at an early stage.
If a sufficient number of mosquitoes are released, the females will be more likely to find a "sterile" male, and a substantial drop in population can be achieved in a remarkably short period.
If mosquitoes are released that are homozygous at 4 loci, a single mass release of 30% can result in over 94% of the mosquitoes in the population possessing at least one copy within 8 generations post-release if the insert does not induce fitness costs.
In this approach, a large number of transgenic male mosquitoes are released to outcompete wild male mosquitoes to mate with female mosquitoes.
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mosquitoes were dissected
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mosquitoes were offered
mosquitoes were reared
mosquitoes were counted
mosquitoes were embedded
mosquitoes were found
mosquitoes were held
mosquitoes were blown
mosquitoes were discarded
mosquitoes were maintained
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mosquitoes were killed
mosquitoes were used
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