Sentence examples for mosaic expression pattern from inspiring English sources

Due to the mosaic expression pattern too few GFP expressing neurones were evident within the InM to assess potential contacts between VGLUT1 terminals and glutamatergic neurones.

The mosaic expression pattern permitted comparison of p16-expressing to nonexpressing cells in the same tissue.

Indeed, Hmgpi was also expressed in entire ES colonies, whereas Zscan4 shows a peculiar mosaic expression pattern in undifferentiated ES cell colonies.

The mosaic expression pattern is defined by the Cre-transgenic mice and crossing them to lines carrying different Cre-dependent transgenes allows their expression in a reproducible fashion.

The first is that the mosaic expression pattern can be reproduced with novel fluorescent- or functional transgenic proteins to allow direct comparison of their effects in the exact same subset of neurons.

Moreover, considering the high level of co-expression of these independent Cre-dependent transgenes and our observation that two different Cre-dependent EGFP-F transgenic lines showed transgene expression in the same sparse neuronal subsets when crossed to the Cre-3487 line, we conclude that the mosaic expression pattern observed is caused by the Cre-3487 line and not by the reporter lines.

The mosaic expression patterns often observed with marker genes (e.g., GFP or LacZ) may be due to the fiber type-specific promoter activities of CMV, CAG, and CK6 promoters [26], as was often shown in muscles following viral vector-based transduction.

Here we present an experimental model that faithfully recapitulates the slow disease progression and the mosaic AE expression pattern characteristic for human t(8 21) CBF AML.

In agreement with previous studies (Michaloglou et al, 2005; Gray-Schopfer et al, 2006), we detected heterogeneous p16 levels and a mosaic p16 expression pattern in cells of nevi (Supplementary Figure S1B and C).

Combining a conditional mouse model that closely resembles the slow evolution and the mosaic AE expression pattern of human t(8 21) CBF AML with global transcriptome sequencing, we find that disease progression was characterized by two principal pathogenic mechanisms.

Interestingly, though, the overall level of Mecp2 expression in male 'Rescue' mice was comparable to that in female 'Non-Rescue' mice (P = 0.17), suggesting that the mosaic Mecp2 expression pattern in male 'Rescue' mice is similar in magnitude overall to that of female 'Non-Rescue' mice.