However, any beneficial effect of diuretics on mortality was lost after adjustment for fluid balance [102].
On the other hand, when PCT was adjusted for CRP, its association with mortality was lost.
However, any beneficial effect of diuretics on mortality was lost after adjustment for fluid balance [ 102].
Additional attenuation was apparent after multiple control and, again, the relations for both IQ variables with CVD mortality was lost.
The significance of CRP with all-cause mortality was lost when serum albumin was added to the model (Additional file 2: Table S2).
Our findings are broadly in line with these previous studies, although our association with mortality was lost after adjustment for the presence of respiratory and cardiovascular conditions and self-assessed health.
However, because the current evidence suggests that the mortality effects of PM are spread over multiple days, examining the effect of PM on a single day results in important information about the effect of PM on mortality being lost and estimates that have a large negative bias (Roberts 2005; Schwartz 2000).
However, in the latest meta-analysis published by the Cochrane Database of Systematic Reviews, signals for mortality reduction were lost and only moderate- and low-level evidence on reduction of morbidity was found, with high risk of overall bias, suspected publication bias and moderate to substantial heterogeneity within the included studies [ 12].
Mortality of patients who were lost to follow-up was obtained by checking municipal registries.
The data were reviewed for internal consistency before annual lockdown, and there were no patients with missing physiological data or who were lost to mortality follow-up.
