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Independent predictors of all-cause mortality were decreasing 6-MWT distance, increasing age, increasing NYHA classification, increasing log NT pro-BNP, decreasing diastolic blood pressure, decreasing sodium, and increasing urea.
In the multivariate analysis, after adjusting for current age, independent factors associated with mortality were decreasing BMI (aRR=6.1; 95% CI: 2.3 16.2, comparing BMI <17.5 kg/m to BMI ≥18.5 kg/m; P<0.001) and increasing WHO clinical stage (aRR=10.2, 95% CI: 3.8 27.2 comparing WHO stage 3 or 4 to WHO stage 1; P<0.001) (Table 4).
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A separate multivariate analysis showed that independent, significant predictors of post-discharge mortality were decreased discharge KPS and earlier fluid resuscitation (<1 hour vs. ≥1 hour) (see Table 5).
Life expectancy at age 65 is prolonging and adult mortality is decreasing, and from this reason human populations live longer.
Such an approach leads to the confusion of demographic knowledge where the question why should be answered (e.g. why the level of mortality is decreasing or the intensity of fertility is increasing) and political intentions where the main goal is what should be done to affect the demographic reproduction.
The incidence of C-spine fractures and mortality more than doubled over the past decade; however, proportional in-hospital mortality is decreasing.
Good News is that despite increase in incidence, cancer mortality is decreasing [2] yet there is great need of new drug discovery and development.
There are encouraging signs that institutional maternal mortality is decreasing, but infectious diseases are a larger proportion of the deaths.
1– 3 The incidence of sepsis in developed nations has been increasing while overall mortality is decreasing, but still remains high.
Forty five percent felt that the incidence of ARDS was declining and 63% felt that mortality was decreasing.
The U.S. studies for this time period of investigation suggested that although incidence was increasing (18), mortality was decreasing (19).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com