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This QTL had an additive effect of −13.8%% in mortality unit.
The data were analysed to determine whether there was any relationship between haemoglobin concentration at ICU admission and any of our outcome measures (unit and hospital mortality, unit and hospital length of stay).
Haemoglobin concentrations ≤10 g/dl on admission to the ICU are associated with an increase in ICU mortality, hospital mortality, unit length of stay and hospital length of stay when compared with patients admitted with haemoglobin concentrations >10 g/dl.
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α is the coefficient controlling density dependent mortality (units of (time -1).
High- or low-mortality unit (HMU/LMU) status was defined specifically as any Trust with high or low outlying mortality at 90 days.
High- or low-mortality unit status of individual Trusts was defined as breaching upper or lower third standard deviation confidence limits on the funnel plot for 90-day mortality.
Twelve units were low-mortality units, of which six were also low outliers at 30 days.
Eight institutions were identified as high-mortality units, including all four units with high outlying status at 30 days.
Although high-mortality Trusts may receive the greatest attention, study of both high- and low-mortality units is needed to understand better how to minimize the risk of death after surgery.
The plotting of mortality at unit level against unit volume for our dataset did not reveal any obvious relations, and we chose thirds because of statistical power and because such an approach is commonly used.
This approach is also justified by evidence that categorisation of neonatal units by intensive care activity correlates more closely with mortality than unit designation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com