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After controlling for the confounder score, the mortality risk difference between arms at baseline was reduced from 29.0 to 4.1 per 1,000 children.
The adjusted absolute mortality risk difference (RD) between linezolid and vancomycin was 0.01% (95% CI −2.1%to2.1%1%; p=0.992; I=13.5%.
The pooled relative risk of death and mortality risk difference were 1.11 (95% CI, 0.95-1.28) and 1.5% (95% CI, -0.7 to 3.8%), respectively, under a fixed-effects model (P = 0.66 and P = 0.65 for heterogeneity, respectively).
The mortality risk difference was significant in all multivariable models except two models that simultaneously adjusted for: (1) comorbidity and surgery type and; (2) underlying diagnosis and surgery type.
Indeed, in our study, smoking status explained about 51% of mortality risk difference between the upper and lower educational groups after adjusting for age, stage, and co-morbidity prior to diagnosis.
An effect of length of stay was also observed in the Dutch study by Stirbu et al [ 6] where the mortality risk difference between recent and earlier migrants in the Netherlands was particularly pronounced in the case of conditions of infectious origin.
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The mortality risk differences of stroke and ischemic heart disease shown in the present study may reflect an excessive risk of Karoshi (death from overwork).
This suggests there are occupation- and industry-based mortality risk differences of stroke and ischemic heart disease for Japanese working-aged men.
However, large educational differences were still reflected in mortality risk differences within twin pairs, thus supporting some degree of independent effect of education.
To analyze differences in estimated pollutant effects by season, we pooled the community-specific estimated mortality risk differences comparing each season to winter in order to obtain national-level 95% PIs for the seasonal differences.
In addition, due to a lack of reliable estimates of incidence and mortality risk differences between screening attenders and non-attenders, it was assumed that women who do and do not attend screening have the same risk of developing and dying of breast cancer.
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