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Take the roughly one-quarter of the estimated mortality reduction was due to "external causes" (injuries, suicide, homicide, complications of medical treatment, and substance abuse).
When the more conservative (7.5%) mortality reduction was used, this upper limit further increased to $3596 per death averted or $150 per life year saved (table 7).
Although it was only in 2007 that the target of universal access (80% of those estimated to be in urgent need of ART receive treatment) was achieved in Thyolo, mortality reduction was evident prior to this year with the largest annual declines, earlier in the study period.
The mortality reduction was larger in the "rural roadside" area (from 13.2 in the pre-ART period to 7.8 per 1000 person-years in ART period 2, a fall of 41%) than in the "rural remote" area (where the mortality rate fell from 6.9 to 6.0 per 1000 person-years, a 13% reduction), with statistical evidence that the time trend was different in the two areas (p = 0.04).
The CRC mortality reduction was calculated as (1 – RR) × 100%.
The mortality reduction was independent of comorbidity category.
Similar(13)
However, the level of mortality reduction is still uncertain.
Inclusion of a specific severity scores, such as SOFA, in the multivariate analysis would allow insights into whether mortality reduction is related to the inclusion of less severe patients.
Five years into the United Nations Millennium Development Goals (MDGs), Goals 4 and 5 on child and maternal mortality reduction were lagging far behind.
Using the pre-ART and ART period 2 mortality rates to construct two survival curves, the impact of the mortality reduction is seen from around age 25.
It is striking that the overall mortality reduction is much larger since an ART clinic opened within the study area, making treatment more accessible than it was during the first year of ART roll-out.
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CEO of Professional Science Editing for Scientists @ prosciediting.com