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Conclusion These results suggest that LV diastolic dysfunction is marginally associated with ICU mortality of septic shock patients.
The potential impact of LV diastolic dysfunction on ICU mortality of septic shock patients may be related to various factors.
The mortality of septic shock, the most severe form of sepsis, continues to be higher than 50% [5, 6].
These findings may help to explain the susceptibility of patients with biliary tract obstruction to the morbidity and mortality of septic complications.
However, at a cutoff Presepsin value of 1926 pg/mL, mortality of septic patients was significantly higher in those with upper levels (Fig. 4b).
Lactate clearance as a goal of early sepsis therapy (in the first 6 hours), compared with central venous saturation, did not reduce the mortality of septic patients [17].
Similar(11)
About 20 years ago, the crude mortality rate of septic shock exceeded 50%% in non-selected populations [1, 2].
The sample size was calculated using the Fisher and Belle formula, with the following variables: mortality rate of septic shock 40 60 %, 95%% confidence interval and 10%% sample error.
An early strategy of quantitative resuscitation enables a decrease in mortality rate of septic patients, but few data are available for prolonged intensive care unit (ICU) strategy [2, 3].
With respect to the high prevalence of comorbidities and high severity scores on admission, the in-hospital mortality rate of septic shock was 45%% in the present unselected cohort.
Beginning with the PROWESS clinical trial of 2001, it was recognised that many of the symptoms of sepsis may be ameliorated by infusion of APC, and mortality rates of septic patients may be significantly decreased.
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