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Hayflick, now 71, is a well-known cell biologist; his discovery in 1961 that normal human cells grown in a test tube simply stop dividing after a specific number of cell divisions, known as the Hayflick limit, in effect introduced the notion of mortality into the biology of aging.
We incorporated mortality into the composite outcome, with the presumption that there may be patients in whom there is such rapid and unexpected disease progression that measurement of some of the other disease progression parameters such as organ dysfunction or hypotension may not be documented prior to patient death.
He'd orchestrated his own mortality into the perfect exit for a performer who'd chosen his name, eschewed gender confines, worn dresses and space suits, and shed one incarnation for another as easily as some of us change socks.
The observed trends might therefore indicate a shift of unavoidable in-hospital mortality into the postdischarge period.
Citizen IDs provided at baseline will enable us to monitor patterns of cohort mortality into the future.
ALERT is the first to incorporate a functional measure, the ADL score, which is associated with mortality, into the predictive equation of short-term adverse hospital outcomes.
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In order to partition the excess mortality into component parts, the ability to identify the excess mortality related to the specific cause of interest in the data is central.
Although improvements in case-finding and in the accuracy of death certification in England and Wales are considered to have had an impact on childhood leukaemia mortality, particularly during the early part of the century, the continued increase in mortality into, and beyond, the 1950s indicates a real increase in incidence (Court Brown and Doll, 1961; Doll, 1989; Swerdlow et al, 2001).
I suppose I got addicted to that sense of finishing, of crossing over from one world (a world of pain and mortality) into another world (the world of love and completion).
Using the NRI method [ 26, 29], we first used the fitted model that used administrative data only, to classify persons' predicted probability of 5-year mortality into low (less the 10%), intermediate 10-500%) or high (more than 50%) risk.
Using the NRI method, we first used the model based on administrative data only, to classify persons' predicted probability of 5-year mortality into low (less the 10%), intermediate 10-500%) or high (more than 50%) risk.
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