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Air pollution has been associated with daily mortality in numerous studies over the past decade.
Inflammatory mediators, particularly elevated serum levels of IL-6 have been associated with frailty and mortality in numerous studies.
Both cold and hot weather have been linked to increased cardio-respiratory mortality in numerous studies [ 18- 20].
Exposure to particulate air pollution has been associated with cardiovascular morbidity and mortality in numerous epidemiologic studies (Brook 2008; Pope et al. 2004).
Weight loss (both volitional and unintentional) is one of the key historical nutrition assessment indicators, which has been associated with long-term mortality in numerous studies [ 9, 11, 27– 29].
Long-term exposure to ambient air pollution has been associated with cardiovascular morbidity and mortality in numerous epidemiologic studies (Dockery et al. 1993; Miller et al. 2007; Pope et al. 2004), but the mechanisms responsible for its observed effects remain poorly understood (Bhatnagar 2006).
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The primary source of vitamin D for most people in temperate climates, particularly people with light-colored skin, is solar ultraviolet-B exposure [ 4, 5], and the amount of exposure to the sun has been found to correlate inversely with cancer mortality and survival in numerous epidemiological studies.
The adverse effects of RBC transfusion on postoperative morbidity and mortality have been demonstrated in numerous studies [ 6, 21– 23].
Sarcopenia measured by normalized total psoas area (NTPA) has been shown to predict mortality and adverse events (AEs) in numerous surgical populations.
Both cold and hot temperatures have been associated with increased mortality risks of respiratory diseases in numerous studies [ 13- 15].
MTH for 12 24 hours in the second time window had been proven to reduce mortality and improve the outcome in numerous patients and animals investigations [ 7, 10, 15].
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