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General symptoms of toxicity and mortality in each group were observed within 24 h.
Crude ICU mortality in the Hb≤9g/dL, Hb≤ 11g/dL, and Hb>11 g/dL groups was 10.9, 7.3 and 7.5%, respectively (p= 0.074), while in-hospital mortality in each group was 26.4, 18.2 and 9.4%, respectively (p < 0.001).
IP vaccination of HSB with two different doses of the ΔsimA mutant (3×104 and 3×106 CFU) resulted in 8% mortality in each group.
The ratio is predicted mortality in each hospital, given its patient mix and hospital-specific effect, divided by the expected mortality in that hospital given the same patient mix and the national average [21].
We then calculated average mortality in each category.
We therefore performed subgroup analyses based on the control group mortality in each study.
95% confidence intervals (CI) for hospital mortality in each group were calculated using the t distribution.
Detailed analyses of mortality in each site have been conducted (14– 14).
Of note, the increased mortality in each of the ACCORD arms was associated with hypoglycemia (17).
We also evaluated the influence of sepsis and the prediction of mortality in each biomarker.
Round-time admission was an independent risk factor for mortality in each of the three ICUs.
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