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Secondary outcomes were healthcare utilisation, body weight, fractures, quality of life, microvascular complications, macrovascular complications, all-cause mortality, harms, cost and cost-effectiveness.
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We determined how baseline PSA level modifies the effects of PSA screening, for both benefits, in terms of reduced prostate cancer mortality, and harms, in terms of overdiagnosis.
It is, then, clear that, despite the difficulty of establishing primary studies in this population, good-quality trials are needed to address the issues of mortality benefits, harms, screening test accuracies and the cost-effectiveness of cancer screening in the transplant population.
To determine extubation success, duration of ventilation, ICU stay, mortality, and harm using cough augmentation techniques compared to no cough augmentation for critically ill adult and paediatric patients with acute respiratory failure.
In terms of mortality, the contrasting harms seem to be similar.
The aim of this paper is to define a balance sheet of benefits (breast cancer mortality reduction) and harms (overdiagnosis) for service mammography screening.
The aim of this study is to define a balance sheet of benefits (breast cancer mortality reduction) and harms (overdiagnosis) for mammography screening programs.
The main objective of this study was to assess the health benefit (mortality reduction) and harms (false positive results and overdiagnosis) attributable to the BCSPBC in Basque women since its implementation in 1996 through 2011.
None of the studies included in the previous reviews of colorectal cancer surveillance have provided any specific details of the harms (mortality or morbidity) resulting from investigating or treating recurrences [ 2, 3].
It is important to separate intermediate outcomes such as potential errors, errors without clinical consequence, and perceptions of safety from definitive patient outcomes such as harmful errors, preventable harm, mortality rates, and risk-adjusted mortality rates.
People who self-harm have been shown to have increased risk of premature death, but little is known about mortality following self-harm in ethnic minority groups.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com